Breakthrough: DNA Data Storage Specification Launched – Paving the Way for Commercialization


March 17, 2024 by our News Team

The DNA Data Storage Alliance has launched its first-ever specifications for DNA-based data storage, providing a framework for encoding information within a DNA data archive and moving towards an interoperable storage ecosystem.

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  • The specifications provide a framework for encoding vital information within a DNA data archive, paving the way for the development and commercialization of an interoperable storage ecosystem.
  • The specifications aim to streamline the initiation of a DNA archive, making it easier to access and retrieve data stored in DNA.
  • The release of these specifications marks a significant milestone in achieving an interoperable DNA data storage ecosystem, with support from industry giants such as Microsoft.


The DNA Data Storage Alliance has recently launched its first-ever specifications for DNA-based data storage. These specifications provide a framework for encoding vital information within a DNA data archive, a crucial step towards the development and commercialization of an interoperable storage ecosystem.

Unlike traditional storage media such as tape, HDD, and SSD, which have fixed structures and controllers, DNA data storage utilizes short strings of DNA called oligonucleotides mixed together without a specific physical ordering scheme. This lack of physical structure poses challenges when it comes to retrieving data and standardizing the process.

To tackle this issue, the SNIA DNA Archive Rosetta Stone (DARS) working group, part of the DNA Data Storage Alliance, has devised two specifications: Sector Zero and Sector One. These specifications aim to streamline the initiation of a DNA archive.

Sector Zero serves as the starting point by providing essential details for the archive reader to identify the entity responsible for synthesizing the DNA and the CODEC used for encoding Sector One. It consists of 70 bases, with the first 35 bases identifying the vendor and the second 35 bases identifying the codec. This information enables access and decoding of data stored in Sector One. Sector Zero’s capacity is small enough to fit into a single oligonucleotide.

Sector One builds upon Sector Zero by including a description of the contents, a file table, and parameters necessary for transferring data to a sequencer. With exactly 150 bases, Sector One spans multiple oligonucleotides and ensures that the main body of the archive is accessible and readable, paving the way for data retrieval.

Dave Landsman, a member of the DNA Data Storage Alliance Board of Directors, emphasized the importance of setting standards and specifications to foster an interoperable DNA data storage ecosystem. The release of Sector Zero and Sector One marks a significant milestone in achieving this goal. These specifications are now publicly available for adoption and implementation by companies operating in this space.

The DNA Data Storage Alliance is led by Catalog Technologies, Inc., Quantum Corporation, Twist Bioscience Corporation, and Western Digital. Notably, Microsoft and other industry giants also support the alliance’s efforts.

Source: SNIA

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Background Information


About Microsoft: Microsoft, founded by Bill Gates and Paul Allen in 1975 in Redmond, Washington, USA, is a technology giant known for its wide range of software products, including the Windows operating system, Office productivity suite, and cloud services like Azure. Microsoft also manufactures hardware, such as the Surface line of laptops and tablets, Xbox gaming consoles, and accessories.

Microsoft website  Microsoft LinkedIn

About Western Digital: Western Digital, established in 1970, is a important data storage solutions provider known for its wide range of hard drives and solid-state drives. Catering to various applications, from personal computers to enterprise storage systems, Western Digital emphasizes data management and security. With a reputation for reliability and innovative solutions, the company has been pivotal in shaping the storage industry. Their products are trusted by individuals, businesses, and data centers worldwide

Western Digital website  Western Digital LinkedIn

Technology Explained


HDD: A Hard Disk Drive (HDD) is a classic data storage device that utilizes spinning disks, or platters, coated with a magnetic material to store and retrieve data. An actuator arm with read/write heads accesses data by moving over the spinning platters. HDDs offer large storage capacities at a comparatively lower cost per gigabyte, making them suitable for applications where massive data storage is required, such as servers and desktop computers. However, HDDs are slower in terms of read and write speeds compared to SSDs due to the mechanical nature of their operation. They are more susceptible to physical shocks and are less energy-efficient due to the need to constantly spin the platters.


SSD: A Solid State Drive (SSD) is a modern data storage device that employs flash memory technology to store data electronically. Unlike traditional hard disk drives (HDDs), SSDs have no moving parts, resulting in significantly faster read and write speeds. This leads to quicker boot times, faster application loading, and smoother overall system performance. SSDs are known for their durability, shock resistance, and energy efficiency, making them ideal for laptops, ultrabooks, and other portable devices. They come in various form factors, including 2.5-inch, M.2, and PCIe cards, and are favored for their reliability, quiet operation, and reduced heat generation





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